The following is an excerpt from the NIH news story released today, “NIH launches free database of drugs associated with liver injury” (http://www.nih.gov/news/health/oct2012/niddk-12.htm
A free source of evidence-based information for health care professionals and for researchers studying liver injury associated with prescription and over-the-counter drugs, herbals, and dietary supplements is now available from the National Institutes of Health. Researchers and health care professionals can use the LiverTox database to identify basic and clinical research questions to be answered and to chart optimal ways to diagnose and control drug-induced liver injury.
LiverTox has a searchable database of about 700 medications available in the United States by prescription or over the counter. Over the next few years, another 300 drugs will be added. The database offers these features:
• An overview of drug-induced liver injury, including diagnostic criteria, the role of liver biopsy, descriptions of different clinical patterns and standard definitions.
• A detailed report of each drug, including background, case study, product package insert, chemical makeup and structure, dose recommendations and references with links.
• An interactive section, allowing users to report cases of drug-induced liver injury to the
LiverTox website. Reports will be automatically forwarded to the Food and Drug Administration's (FDA) MedWatch program. MedWatch allows the public and health care professionals to report adverse events, product defects, or product use errors. The FDA uses the information to monitor product safety.
The database will be updated regularly with information about drug-induced liver injury as well as new drugs and new concepts. LiverTox welcomes input and comments from users through the website, at http://www.livertox.nih.gov